When Giuliana turned 35, the couple decided to start trying but without much luck.

She continued, “I always say how I chased my career instead of chasing guys.

And everybody was patting me on the back.

Bill and Giuliana Rancic posing for photos

However, “View” star Whoopi Goldberg couldn’t quite empathize with Giuliana’s reservations about weight gain.

She added, “And there’s no buts.

If you want a baby, this is what you have to do.

Giuliana and Bill Rancic posing for photos

So you have to make that decision,” (viaE!

Nonetheless, the TV star managed to gain some weight, but she still couldn’t get pregnant.

But they persevered through and continued with the IVF treatments.

Giuliana, Duke and Bill Rancic posing for photos

In fact, in 2010, Giuliana toldUs Weeklyshe would sometimes take 63 IVF injections a month.

Unfortunately, their second attempt also failed.

The reality star described it as “the biggest kick in the stomach” to Health magazine.

Thankfully, it wasn’t long before the Rancics' situation finally got better.

Giuliana continued, “She was so devoted and such a good person.

There are so many women out there who want to help who are such amazing women.

They’re like angels.”

Sadly, their surrogate, Delphine, miscarried the baby nine weeks into the pregnancy.

But, on New Year’s Eve 2014, they learned that their surrogate had suffered a miscarriage.