Read on to remember the “Frasier” stars we’ve sadly lost.

In an interview withFox Newsshortly before his death, Mahoney candidly discussed overcoming cancer twice previously.

Mahoney gravitated toward acting fairly late in life.

The cast of “Frasier”

“I just felt I had to try acting one more time.

And if I fail, I fail,” he continued.

As the dogs' trainer Mathilde DeCagney told the Post, father and son didnotget along.

John Mahoney smiling

Like his dad, Enzo lived until age 16,dyingin 2010.

Joked Mahoney: “He was a temperamental actor as far as I’m concerned.”

AsDeadlinereported, Kramer died in early 2020 at age 74.

Kelsey Grammer, Moose

Other notable roles include a multi-episode arc on “The Sopranos.”

In a 1990 interview withThe New York Times, Loggia explained his career longevity.

“So I never wear out my welcome.

Marsha Kramer looking to the side

First seen in the series' eighth season, Auberjonois portrayed Frasier’s Harvard professor, Dr. William Tewksbury.

The bar’s owner, Duke, was frequently referenced throughout the series.

According to LaMotta’sIMDb page, he died in 2014 at the age of 75.

Bob Hoskins with a cigar

Among the many, many roles listed in hisIMDb creditsare a brief guest spot on “Frasier.”

Sheppard played Mr. Drake, the club’s president.

As a result, Frasier agrees to testify against his brother in the trial.

Robert Loggia wearing blue stripes

Stan Jablonski, who took over for veteran cop Sgt.

Phil Esterhaus after the actor who portrayed him, Michael Conrad, died of cancer in 1983.

Prosky, who died in 2008 at age 77, made a memorable appearance on “Frasier.”

Rene Auberjonois looking to the side

In hisguest spot, Prosky played famously reclusive author T.H.

Houghton (loosely based on “A Catcher in the Rye” writer J.D.

More than a decade after that series wrapped, Stiers made a guest-starring appearance on “Frasier.”

Alice Playten wearing black

Later serving for four terms as United States Senator, Glenn was also a “Frasier” guest star.

She ultimately brings Glenn onboard as a replacement narrator, which irks Frasier to no end.

“Frasier” isn’t just Glenn’s most memorable TV guest starring role it’s his only one.

John LaMotta on Frasier

Of the more than 100 stars who called in, many of them are sadly no longer with us.

“Superman” star Christopher Reeve, whodied at 52 in 2004, called in to discuss his agoraphobia.

to the Woody Allen-directed “Mighty Aphrodite.”

William Morgan Sheppard wearing glasses

Murphydied in 2014at age 89.

He died at 88 in 2010 (viaThe Hollywood Reporter).

Donald O’Connor wearing yellow

Robert Prosky wearing a red tie

David Ogden Stiers wearing glasses

John Glenn in his official NASA photo

Mary Tyler Moore and Eddie Van Halen, split image

Bill Gratton being interviewed

Jack Sydow and Rosemary Murphy in Frasier