“General Hospital” is renowned for being the home of many soap opera supercouples.

Tragic love stories are almost as popular as successful ones on soap operas.

For every happy couple, there’s another one who just can’t seem to catch a break.

Finola Hughes and Ian Buchanan talking

Dominique first met Scott when they were both working for Deception perfume.

Despite the lack of support, Robin was enamored with Stone from the jump.

As Stone’s illness worsened, Robin acted as his caretaker until he died.

Kin Shriner and Shell Danielson getting married

They met when Emily returned to Port Charles after recovering from temporary paralysis.

Eventually, her marriage to Zander was ruined after she had an affair with Nikolas.

Mary Bishop (Catherine Wadkins) took him in, but Emily eventually rescued him.

Michael Sutton and Kimberly McCullough

Duke and Anna first met when he was working as a nightclub owner.

Sadly, Julian Jerome (William deVry) presumably killed Duke before he could reconcile with Anna.

However, after Victor Cassadine (Thaao Penghlis) imprisoned them, they confessed their feelings for one another.

Tyler Christopher and Amber Tamblyn hugging

Eventually, Nathan was able to win Maxie over at the Nurses' Ball and they reunited.

However, all was forgiven when she returned and soon became pregnant.

Nathan died with Maxie by his side, and all she had left was their child together.

Finola Hughes looking at Ian Buchanan

Kirsten Storms and Ryan Paevey kissing