For years, it was America’s longest-running primetime show.

Over the course of its run, it picked up a staggering 124 Emmy nominations and 23 wins.

Curious to see what happened to your favorite “ER” stars?

George Clooney in ER

Let’s take a look at what they’re up to today.

He was in 180 episodes from 1994 to 2008.

In 1998, he took home a Golden Globe for his work on “ER.”

Anthony Edwards then and now split

On top of all that, he’s also done some directorial work and acted on Broadway.

Of course, after the NBC procedural, the actor became one of the most recognizable names in Hollywood.

““And it changed my career.”

George Clooney then and now split

The two wed in 2014 and went on to welcome two children.

She turned down a mind-blowing $27 million.

People in her inner circle urged her to sign the contract, but it didn’t feel totally right.

Julianna Margulies then and now split

After “ER,” Margulies' career continued to grow.

In 2021, she released a memoir titled “Sunshine Girl: An Unexpected Life.”

In 2017, he also appeared in “Logan.”

Eriq La Salle then and now split

La Salle’s found a lot of success on the other side of the camera, too.

And by all accounts, he’s more than content with where his career has taken him.

“I just thought, I can’t be here for 80 hours a week and miss this.

Noah Wyle then and now split

And I quit,” he said.

Wyle also got into writing and directing, even directed five episodes of “Leverage.”

She had previously appeared in small guest roles in a variety of TV shows.

Laura Innes then and now split

After leaving the show, Innes continued acting, but didn’t land many more big roles.

She went on to take what she had learned with her into her directing career.

Deezer D starred in his last film, “Courting Mom and Dad,” in 2021.

Deezer D on ER and in 2014

He died that same year from a heart attack at the age of 55.

New music was released just days after his death.

For that film, Visnjic was thrilled to be immersed in the “real” setting.

Goran Visnjic then and now split

We shot in real villages, I drove a real car from that age,” he toldPremiere Scene.

She went on to add, “It was a wonderful experience, we loved it.”

Ceron continued acting on TV.

Laura Ceron then and now split

Before that, she was in six episodes of “Shameless.”

To this day, “ER” remains very close to her heart.

“That show was just as funny on set as ‘NewsRadio,'” she said.

Maura Tierney then and now split

You may also remember her for her beautiful voice, which she showcased on the series.

“They let me sing, that was a wonderful thing,” she toldWPEA Radioin 2009.

Freeman’s long career has involved dozens of guest roles in a variety of TV shows.

Yvette Freeman then and now split

Like many of her “ER” colleagues, Freeman cherishes the time she spent on the primetime soap.

“I was very honored and a very blessed actress to have 15 years of steady work.

That doesn’t happen in being an actor,” she said on WPEA Radio.

Emily Wagner then and now split

“It’s a good show, I’m still, still proud of it.”

She was still early in her career when she joined “ER.”

“ER” was far and away her first major production, and she felt the stakes right away.

Alex Kingston then and now split

So I had so much pressure on me," she said.

After “ER” finished, Wagner found work as a writer, fitness teacher, and acting teacher.

In recent years, she’s pulled back on the acting grind.

Sherry Stringfield then and now split

As of 2023, her last acting role was in 2017.

But that’s not to say she stopped making big moves.

In 2018, Stringfield sold her house in Malibu for over $3 million.

Abraham Benrubi then and now split

Not a bad haul.

In addition to his whopping 137 episodes of the primetime soap, he’s done loads of other work.

He’s also taken on dozens of guest roles on TV.

Mekhi Phifer then and now split

His post-“ER” film credits include the “Divergent” trilogy.

As for the acting gig that’s nearest and dearest to Phifer’s heart?

That question is easier asked than answered.

Parminder Nagra then and now split

“You know, there’s not one favorite one.”

However, it’s clear Phifer remembers his time on “ER” fondly.

I’m really proud of ‘Torchwood,’ as I was with ‘ER.'"

Troy Evans then and now split

“I’m still proud of the film,” she toldThe Guardianin 2021.

“It’s probably what I’m most recognised for.”

She joined the cast of “ER” one year after the hit indie flick was released.

Linda Cardellini then and now split

When it comes to choosing roles, Nagra likes any opportunity to do something new.

“I don’t often get the chance.”

He continued on until the series finale.

Paul McCrane then and now split

“I am really comfortable with a nice little taste here and there.

As the saying goes, ‘Take it easy, but take it.’

I’ll take it.”

Ming-Na Wen then and now split

Looking back at his career so far, it seems that has been his motto all along.

After “ER,” her career continued to grow.

She has also appeared in Oscar-winning films “Green Book” and “Brokeback Mountain.”

Lyn Alicia Henderson smiling

Suffice to say, she’s one of the biggest stars to come out of County General.

In the 2020 live-action remake of “Mulan,” she delighted fans by making a surprise cameo.

Wen was on “ER” for six years before leaving in 2004.

Ellen Crawford smiling

Since then, she has climbed aboard a number of huge franchises.

In 2023, Wen got her star on the Hollywood Walk of Fame.

“All I’m doing is living out my biggest nerd dreams,” she toldVarietyat the time.

Lily Mariye smiling

Nerdy or not, her career is certainly a big deal.

Henderson enjoyed her time on “ER,” largely thanks toGeorge Clooney.

He didn’t say those words but that’s how you felt when you came to the set."

Crawford actually worked with her real-life husband, Mike Genovese, on “ER.”

He played Officer Al Grabarsky, who had a relationship with Crawford’s character, for 12 episodes.

Apparently, the producers wrote the part just for him he didn’t even need to audition.

Plus, they didn’t even tell Crawford about the plot line in advance.

“They didn’t even ask me, I mean, it wasn’t my doing!”

she later laughed on the"Setting the Tone"podcast.

As Nurse Lily Jarvik, she was a constant figure in the emergency room.

“If I’d listened to other people, I would have just stopped.”