And while each could boast a larger-than-life career, no clashing egos were involved.

“We became, like, instant friends,” Roberts said.

“This old thing?”

Julia Roberts and George Clooney

Roberts quipped at the start of her introduction during the ceremony (viaYouTube).

I’m here for Gladys Knight, can’t you tell?"

He’s the best combination of gentleman and playmate," she continued.

Julia Roberts wearing George Clooney dress

Moreover, both have built their own happy families.

Roberts has been married to cinematographer Danny Moder since 2002, with whom she has three children.

And in 2017, Clooney and his wife, Amal (nee Alamuddin), had fraternal twins.

Julia Roberts and George Clooney

We just keep stitching our lives closer together," Roberts said.

Clooney even revealed the nickname his twins have for Roberts to theNew York Times: Aunt Juju adorable!

But it’s not just their two families that enjoy the stars' friendship.

Their chemistry is palpable to their co-stars, too.

Theylovemaking each other laugh, and it’s the best thing to be around."

And as far as we’re concerned, it’s pretty great to watch, too.